Pharmaceutical Technology

Controlled extended octenidine release from a bacterial nanocellulose/ Poloxamer hybrid system

Dr. Dagmar Fischer, Institute of Pharmacy, University of Jena

The research group used bacterial nanocellulose for the production of wound dressings. In the case of octenidine, an antiseptic used in wound treatment, it has been possible to create a hybrid system by incorporating poloxamer polymers in the form of micelles or gel structures in nanocellulose, which can release active substances in the form of modern wound dressings. In clinical practice, this means fewer dressing changes and thus more patient compliance, cost and time savings. The material also has outstanding properties in terms of water absorption, softness and flexibility, combined with excellent biocompatibility. The result is a controllable drug carrier system for long-lasting dermal wound treatment.